RAD 140 vs RAD 150: Which SARM Is Right for You? A Comprehensive Comparison

Selective androgen receptor modulators (SARMs) have become increasingly popular in the fitness and bodybuilding communities due to their ability to promote muscle growth without the harsh side effects of anabolic steroids. Among the most talked-about SARMs are RAD 140 (Testolone) and RAD 150 (Benzoate Testolone).

But with both compounds promising anabolic benefits, the key question is: Which one should you choose? In this article, we offer an in-depth comparison of RAD 140 and RAD 150 to help you make an informed decision based on scientific research, anecdotal evidence, and personal goals.

What is RAD 140 (Testolone)?

RAD 140 is a nonsteroidal SARM developed to mimic the effects of testosterone while avoiding the negative side effects associated with traditional anabolic steroids. It selectively binds to androgen receptors in muscle and bone tissue, triggering anabolic activity such as:

• Increased lean muscle mass
• Enhanced strength and power
• Improved fat loss
• Better recovery and endurance

RAD 140 is widely studied and has demonstrated promising results in preclinical research, with strong anabolic effects and relatively mild androgenic activity (source).

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What is RAD 150 (Benzoate Testolone)?

RAD 150 is a newer, chemically modified version of RAD 140. It contains a benzoate ester attached to the base molecule, designed to:

• Improve bioavailability
• Extend the compound’s half-life
• Potentially enhance muscle-building effects

While RAD 150 shares a similar mechanism of action—binding selectively to androgen receptors the ester modification may lead to longer-lasting activity and smoother hormonal fluctuations. However, clinical data on RAD 150 is currently limited, and most information comes from user experiences and industry speculation.

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RAD 140 vs RAD 150: Key Differences

Feature	RAD 140 (Testolone)	RAD 150 (Benzoate Testolone)
Chemical Structure	Base SARM compound	RAD 140 + benzoate ester
Bioavailability	High, but rapidly metabolized	Claimed higher due to esterification
Half-Life	~16–20 hours	Believed to be longer
Muscle Growth	Proven effective	Anecdotally stronger gains
Strength Gains	Strong	Potentially superior
Onset of Effects	Quick onset	Slower, more sustained
Side Effects	Well documented	Less known, may persist longer

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Side Effects and Safety

Both RAD 140 and RAD 150 interact with the endocrine system and can suppress natural testosterone production. Common side effects may include:

• Testosterone suppression
• Mood fluctuations
• Acne or oily skin
• Possible estrogen imbalance
• Changes in cholesterol levels

RAD 140 has more established safety data, while RAD 150 may carry prolonged side effects due to its extended half-life.

For an overview of SARM-related risks, see the U.S. Pharmacist’s review.

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Studies of RAD 140 vs. RAD 150

RAD 140 has been the subject of multiple preclinical studies, including trials on its anabolic-to-androgenic ratio, neuroprotective benefits, and cancer cell inhibition (PubMed). In contrast, RAD 150 lacks peer-reviewed clinical or preclinical research, making it more experimental.

Until RAD 150 undergoes similar scrutiny, its benefits and risks remain speculative.

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Dosage and Cycling

Compound	Common Dosage	Cycle Length
RAD 140	10–30 mg/day	6–8 weeks
RAD 150	5–10 mg/day (limited data)	6–8 weeks

Both compounds should be followed by a post cycle therapy (PCT) to restore natural testosterone production and minimize hormonal disruption.

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Post Cycle Therapy (PCT)

Why it matters: SARMs suppress the body’s natural production of testosterone. Without a proper PCT, users risk prolonged hormonal imbalance, low libido, fatigue, and muscle loss.

Common PCT agents:

• Clomid (Clomiphene Citrate)
• Nolvadex (Tamoxifen Citrate)

PCT Duration: 4–6 weeks, depending on the severity of suppression and user recovery speed.

For a deeper guide, Examine.com offers objective summaries on PCT protocols and hormone restoration strategies.

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User Experiences and Anecdotal Evidence

RAD 140

• Frequently praised for rapid muscle and strength gains
• Users report testosterone suppression, sometimes requiring aggressive PCT
• Side effects include mood changes and gynecomastia when not properly managed

RAD 150

• Still gaining popularity, with limited user feedback
• Some claim greater endurance and smoother hormonal shifts
• Others report stronger suppression and longer side effects compared to RAD 140

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Which SARM Is Right for You?

Goal/Experience Level	Recommended SARM
Beginner	RAD 140 (well-documented, safer)
Experienced User	RAD 150 (if willing to experiment)
Shorter Cycles	RAD 140
Longer-Lasting Effects	RAD 150
Risk-Averse Individuals	RAD 140

Choosing between RAD 140 and RAD 150 ultimately depends on your experience level, risk tolerance, and desired outcomes. If you value a compound with research backing and predictable results, RAD 140 is the safer bet. If you’re looking for potentially enhanced, longer-lasting effects and are comfortable with experimental use, RAD 150 might appeal to you.

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Conclusion

Both RAD 140 and RAD 150 offer compelling benefits for muscle growth and performance enhancement, but they cater to different types of users. RAD 140 is better supported by research and anecdotal evidence, making it ideal for those seeking reliability. RAD 150, while promising, is still in the early stages of understanding, requiring careful experimentation and close monitoring.

Regardless of which SARM you choose, always prioritize health and safety, use responsible dosing practices, and follow through with a proper PCT. Speak with a medical professional before beginning any cycle.