Phentermine and Antibiotics – Does it have an effect on antibiotics?

  • By: jacob foxx
  • Date: April 1, 2023
Phentermine and Antibiotics

Few studies have been done on what might happen if you take phentermine with antibiotics, so doctors have different ideas about what might happen.

Despite this ambiguity, it has been found that combining Amoxil and Adipex does not result in direct drug interactions.

But it’s important to know that phentermine can make a person less hungry, which can make the bad effects of amoxicillin worse if they don’t eat or drink enough.

A 2017 study in The BMJ Case Reports shows that taking phentermine and penicillins together can cause acute interstitial nephritis, which is a type of renal failure caused by inflammation.

Because of these possible side effects, it’s important for both doctors and patients to be careful when using these drugs together.

If your physician has prescribed you antibiotics, does that imply that you should immediately discontinue use of phentermine? What are some potential outcomes that could result from combining the use of these two substances?

Keep reading down below to find out more information.

Can Phentermine and Antibiotics Be Used Together?

The question of whether phentermine and antibiotics can be used together remains a topic of debate among medical professionals.

Studies have been done, but the results have been contradictory, so many people aren’t sure if mixing the two medicines is safe.

When the two are used together, there is a risk of AIN, which is drug-induced renal failure that can have serious effects.

AIN can cause you to feel tired, throw up, feel sick, and have pain on the left side of your lower abdomen.

Due to the potential risks involved, it is critical to inform your doctor about all medications you are taking, and never stop taking phentermine without first consulting your physician.

Doing so could cause serious and possibly fatal side effects like seizures, stroke, nerve damage, congestive heart failure, or cardiac arrest.

Do Antibiotics Interfere with the Benefits of Phentermine?

Recent studies have investigated the potential interaction between antibiotics and the popular weight loss drug, phentermine.

Specifically, research has shown that ciprofloxacin can reduce the metabolism of phentermine, which can have both positive and negative effects.

On one hand, this reduction can decrease the risk of dangerous and prolonged effects of the drug, such as heart disease.

On the other hand, this decrease can also cause the drug to work less well, making it less effective at suppressing appetite and giving you more energy.

Given these risks, it is advised to avoid taking ciprofloxacin and phentermine together.

Does Phentermine Interact with Antibiotics?

When prescribing medication, doctors have known for a long time how important drug interactions are.

Studies have shown that the use of phentermine-topiramate can affect the metabolism of antibiotics such as amoxicillin, clarithromycin, and lansoprazole.

In real life, this means that the antibiotic might not work as well, which could lead to antibiotic resistance and the need for stronger drugs.

Being aware of potential drug interactions is crucial to ensuring the effectiveness of prescribed medication, and medical professionals should always consider the potential risks and benefits of prescribing multiple drugs at once.

Potential Phentermine And Antibiotics Risks


Overdosing on medication can be a serious matter, as it can lead to uncomfortable symptoms, chronic physical and mental disturbances, and in more severe cases, even death.

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While antibiotic overdose rarely results in fatalities, it can still cause distressing side effects like stomach upset and diarrhea.

Conversely, a phentermine overdose can be dangerous, with rapid breathing, abdominal cramps, tremors, confusion, restlessness, and hallucinations as potential symptoms.

If left unattended, severe cases of phentermine overdose can even lead to convulsions, coma or death.

Therefore, whenever an overdose is suspected, it is important to seek immediate help by calling the emergency services or the Poison Helpline.

Side Effects

Healthcare professionals have been worried about what might happen if antibiotics and phentermine are taken together.

Recent research suggests that there may be an indirect link between the two medications, which could increase the risk of side effects.

The exact cause of this interaction is still not known, but it is thought that a change in metabolism may be to blame.

If you’re also taking antibiotics, keep an eye out for the following phentermine side effects:

  • Agitation
  • Altered drug metabolism
  • High blood pressure
  • Headache
  • Dry mouth
  • Constipation
  • Diarrhea
  • Insomnia


Abuse is a serious issue that affects many people worldwide. Although it can take many forms, drug abuse is one of the most common.

Phentermine is a stimulant that is classified as a schedule II drug due to its potential for dependence and abuse.

Unfortunately, people who want to escape from emotional or physical pain can become addicted to the “high” that comes with its use.

While antibiotics are not commonly used recreationally, their misuse is still a form of drug abuse.

When antibiotics are used more than necessary, bacteria that are resistant to antibiotics can grow. These bacteria have to be treated with stronger drugs, which is bad for both the person and society as a whole. 

What Is a Better Weight-Loss Medication Than Phentermine?

When it comes to weight loss, it’s important to consider the potential risks and side effects of medications.

While phentermine may be an FDA-approved weight-loss drug, it may not be the best option for everyone due to its notable risks.

If you are looking for an alternative, PhenQ is a dietary supplement that can help suppress your appetite and give you similar results without any risks.

click to find out more about PhenQ

The main ingredient in PhenQ, a-LACYS RESET, is patented and has been shown to help people lose weight in a natural way.

With PhenQ, individuals can safely and effectively reach their weight-loss goals without compromising their health.


Can You Take Phentermine With Other Medications?

Yes, Phentermine can be taken with other medications. However, it is important to talk to your doctor before combining Phentermine with any other drug or supplement.

There may be some potential interactions that could cause serious side effects, particularly if you are taking blood pressure medication, antidepressants, sedatives, antihistamines, and muscle relaxers.

Be sure to tell your doctor about all medications and supplements that you are using before taking phentermine.

What Medications Should You Avoid While Taking Phentermine?

Phentermine is a prescription weight-loss medication used to help people lose weight. It is important to know what medications should not be taken with phentermine in order to avoid potential side effects and interactions.

Below are some medications that should not be taken with phentermine:

  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants
  • Other stimulants, such as amphetamines or caffeine
  • Blood pressure medications, including beta blockers and diuretics
  • Insulin or other diabetes medications
  • Seizure medications, such as phenytoin or carbamazepine
  • Cold or allergy medicines containing decongestants, such as pseudoephedrine or phenylephrine
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It is also important to talk to your doctor before taking any new medications while on phentermine. This includes over-the-counter drugs, vitamins, and herbal supplements. Taking these together may increase the risk of side effects.

Can I Combine Phentermine with Amoxicillin?

Many people wonder if they can combine phentermine with amoxicillin. The answer is yes and no. While there are no direct drug interactions between the two, it is important to note that Phentermine can boost the effects of Amoxicillin, as well as increase the risk of side effects.

It is always best to consult your doctor before combining any medications, including phentermine and amoxicillin. Your doctor can help you decide what to do next based on your individual needs and health history.

Additionally, it is important to be aware of other drugs that may interact with Phentermine, such as metformin, sertraline, or albuterol.

Can You Take Phentermine And Ibuprofen Together?

It is possible to take phentermine and ibuprofen together; however, it is important to be aware of the potential drug interactions between the two medications.

Ibuprofen can make the side effects of phentermine worse, like raising your blood pressure and making you feel anxious.

It is recommended that you talk with your healthcare provider or pharmacist before taking phentermine.


Phentermine, a popular weight-loss drug, has been linked to serious health complications.

While it may work for some individuals, it is important to be aware of the potential risks and interactions with other medications.

It is crucial to speak with your doctor before starting any new medication, especially one with potentially severe side effects.

Similarly, antibiotics also have the potential to cause serious side effects. It is imperative that you follow your doctor’s instructions and only take antibiotics as prescribed.

Your health is of the utmost importance, and it is essential to prioritize the safe and responsible use of medication.

I'm Jacob Foxx, a proud native of the outskirts of Chicago, Illinois. I was enamored with the expansive Star Trek universe and its promise of cutting-edge technology and space travel from a young age. This early fascination with science fiction sparked my imagination and laid the foundation for my writing career. Alongside my love for the cosmos, I developed a passion for fitness in my formative years.

This dual interest in the world of tomorrow and the pursuit of physical health has greatly informed my writing, allowing me to explore themes of human potential and the future of our species. As an author, I strive to blend these passions into compelling narratives that inspire readers to dream and to push their own boundaries.

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